Question Details

(Solved) (Latest ver. Aug 2020) - Intracellularly recording from pyramidal cells in a mouse

Brief item decscription


Item details:

Question:

I am recording intracellularly from the neocortex of a mouse. If I place my electrode on one set of pyramidal neurons (Layer 2) and add fenfluramine (a serotonin uptake blocker), whithin 5 minutes the neurons produce GREATER amount of action potentials. But when I place fenfluramine while recording from another set of pyramidal cells (Layer 5 for example), the neurons showed a DECREASE in AP's (action potentials) after 5 minutes of treatment. How is this possible for one drug to affect similar cells in completely different methods?

Please offer any feedback - if you feel that I haven't explained the question well enough, or if you aren't certain what I am looking for, please let me know. I am looking for help getting started on this and am hoping that you can provide some guidance.

 







About this question:
STATUS
Answered
QUALITY
Approved
ANSWER RATING

This question was answered on: Sep 16, 2020

PRICE: $11.5

Solution~0001311.zip (18.37 KB)

Buy this answer for only: $11.5

Pay using PayPal (No PayPal account Required) or your credit card. All your purchases are securely protected by PayPal.
SiteLock

Need a similar solution fast, written anew from scratch? Place your own custom order

We have top-notch tutors who can help you with your essay at a reasonable cost and then you can simply use that essay as a template to build your own arguments. This we believe is a better way of understanding a problem and makes use of the efficiency of time of the student. New solution orders are original solutions and precise to your writing instruction requirements. Place a New Order using the button below.

Order Now